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Category Archive: PGT US, Porcine Circovirus, Zoetis News Center

PCV2 vaccine for swine elicits strong cell-mediated immune response

DISCOVERIES, Issue 9: A porcine circovirus type 2 (PCV2) vaccine from Zoetis produces a robust and lasting cell-mediated immune response.

Johnson: Five steps for porcine circovirus control

Some breed-to-wean farms that have been vaccinated for porcine circovirus (PCV) have experienced breakdowns in their control of the virus. Clayton Johnson, DVM, outlines his top five steps for...

Field studies demonstrate safety of Fostera® Gold PCV MH vaccine

DISCOVERIES, Issue 5: Fostera® Gold PCV MH, the inactivated vaccine from Zoetis developed to provide the broadest protection available against porcine circovirus type 2 (PCV2), has been demonstrated...

High prevalence of PCV2 recombinants highlights importance of broad vaccine coverage

DISCOVERIES, Issue 21: A recent analysis of porcine circovirus type 2 (PCV2) genetic sequences shows that up to 25% of field strains are recombinants of diverse genotypes, highlighting the importance...

Processing fluids provide an option to monitor PCV2 and PCVAD

Effective PCV2 control relies on vaccination of healthy pigs before they become infected. This goal cannot be accomplished in unstable herds whose sows give birth to viremic pigs.

Rate of PCV2 recombination not widely recognized

TOOLBOX, Issue 16: An interview with Meggan Bandrick, DVM, PhD Associate Director, Global Biologics Research, Zoetis

Why monitor swine herds for PCV2?

TOOLBOX, Issue 23: Noel Garbes DVM, senior technical services veterinarian, Zoetis, recently talked with editors of Pig Health Today about monitoring swine herds for PCV2.

Comparing PCV2 gilt vaccination protocols and progeny status

Porcine circovirus type 2 is the principal etiological agent of porcine circovirus associated disease (PCVAD), which can cost producers an estimated $3 to $4 per pig.

Chimera technology offers better path to protection for PCV2

DISCOVERIES, Issue 6: When PCV2 first became a problem in US swine herds, scientists looked at taking the immunogenic capsid gene from PCV2 and cloning it into the backbone of nonpathogenic PCV type...

Diagnostic experts: PCV3 is common in US swine herds

PCV3 was first reported in 2016, but appears to have been present in swine populations decades prior to that time. PCV3 strains are similar to one another but are very different from PCV2.

PCV3 is ‘absolutely’ a pathogen but proceed with caution

Porcine circovirus type 3 (PCV3) is “absolutely” a pathogen but merely finding the virus isn’t enough to conclude it’s the cause of disease.

It’s back: Clinical outbreak of PCV2 in genetic herds reported

A clinical outbreak of porcine circovirus type 2 (PCV2) occurred this past winter in otherwise healthy, well-vaccinated herds, Clayton Johnson, DVM, of Carthage Veterinary Service, told Pig Health...

Processing fluids’ effectiveness in monitoring PCV2 in sow herds

Vaccines have provided effective control options for PCV2, but vertical transmission remains a challenge for some farms.

Processing fluids hold promise for PCV2 testing on sow farms

Understanding the pathogen status of a sow herd helps determine the prevention, control and treatment options to protect piglets as they grow. For PCV2 there is no treatment; however, vaccination is...

The changing face of PCV: Virus experts compare notes on evolving pathogen in US swine herds

Clinical disease due to porcine circovirus type 2 (PCV2) has been dramatically reduced thanks to vaccination, but concern remains about the persistence of PCV2 subclinical infection, even in...

Two-dose Fostera® Gold PCV MH regimen yields performance advantages

DISCOVERIES, Issue 16: Pigs in a study that received two doses of Fostera® Gold PCV MH, the new Zoetis vaccine for PCV2 and M. hyo, had numerically fewer reactions, less morbidity, less mortality.

Evolution of PCV2 virus, need for broader coverage spurred development of Fostera® Gold PCV MH

DISCOVERIES, Issue 7: Compelling scientific evidence indicating the need for an updated porcine circovirus type 2 (PCV2) vaccine was the driving force behind the development of Fostera® Gold PCV...

Fostera® Gold PCV MH protects pigs against PCV2a, PCV2b and M. hyo for at least 23 weeks

DISCOVERIES, Issue 8: Fostera® Gold PCV MH is the only USDA-licensed vaccine that protects pigs against porcine circovirus (PCV) type 2a, PCV2b and M. hyo for at least 23 weeks.

Tale of two viruses: PCV3 impact unknown while PCV2 continues to evolve

Genetic sequencing demonstrates that porcine circovirus type 3 (PCV3) is significantly different from PCV2, but otherwise little is known about the virus.

Scientist ‘pops the hood’ on US pork industry’s newest vaccine for PCV2

What is “cell-mediated immunity” and how does it affect vaccine performance? Are two PCV2 genotypes necessarily better than one? And what does a monster from Greek mythology have to do with...

Epitope-comparison study illustrates broad coverage of Fostera Gold® PCV MH against PCV2 viruses

DISCOVERIES, Issue 4: Swine disease specialists speculated that a PCV2 vaccine containing two genotypes — PCV2a and PCV2b — would significantly improve the coverage provided against PCV2...

PCV3: A challenge independent from PCV2

Anyone involved in raising pigs is aware of PCV2, but new on the scene is porcine circovirus type 3 (PCV3). Although the two viruses are both circular DNA viruses in the same family, they are...

Large field trial showed Fostera Gold® PCV MH was effective against prevalent PCV2d genotype

DISCOVERIES, Issue 3: A large, commercial field trial conducted with Fostera® Gold PCV MH showed it was also effective against PCV2d, the most prevalent genotype of the virus circulating among US...

Pigs vaccinated with Fostera®PCV MH equally protected, weighed nearly 8 pounds more in large comparison trial

DISCOVERIES, Issue 1: Pigs vaccinated with Fostera® PCV MH were equally protected against porcine circovirus (PCV) type 2d as well as Mycoplasma hyopneumoniae (M. hyo) and weighed 7.78 pounds more...

New Fostera Gold PCV vaccines: Broadest coverage for PCV2 viruses

TOOLBOX, Issue 8: Rick Swalla, DVM, recently talked with editors of Pig Health Today about the pork industry’s first vaccine to include two genotypes of porcine circovirus type 2 (PCV2) and the...

US pork industry’s first vaccine with two PCV2 genotypes announced at AASV

The US pork industry’s first vaccine to include two genotypes of porcine circovirus type 2 (PCV2) — 2a and 2b — was announced on the first day of the American Association of Swine...

PCV MH vaccines provide equal protection in study, but lung lesions, ADG, final weight differ

Three porcine circovirus (PCV) vaccines compared in a recent study equally protected pigs against PCV type 2d and Mycoplasma hyopneumoniae, but there were some significant differences in gross...

Colostrum may be best sample for PCV2 on sow farms

Colostrum may be the best sample to test for determining whether porcine circovirus type 2 (PCV2) is present in sow herds, according to researchers at Iowa State University (ISU).

PCV3 may be a bigger problem than expected

The emergence of novel porcine circovirus-3 (PCV3) in US pig herds requires closer research into whether the disease is commonly circulating in the country’s hog population, scientists say.

Using diagnostics to optimize PCV2 vaccination

By Don McDermid, DVM, Swine Veterinary Services Manager, Zoetis, Kirkland, Quebec, Canada


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